Partner

  • McGill University

Context

“Motoric Cognitive Risk” syndrome (MCR) is a pre-dementia syndrome that leads to subjective cognitive issues and a slow walking gait. MCR syndrome is a transitional syndrome, between normal aging and mild cognitive impairment (MCI). MCR and MCI form an intermediate stage between physiological decline linked to the normal aging process and pathological decline caused by major neurological conditions (dementia). Cognitive performance is generally used to classify the various pre-dementia stages. There is a lack of information in relation to the cognitive profiles of patients suffering from MCR syndrome and the extent to which it overlaps with mild cognitive impairment. There is currently no study that compares the cognitive profiles of patients suffering from MCR and MCI. Because MCR appears to be a better predictor of vascular dementia, rather than Alzheimer’s disease, and because vascular dementia is characterized by executive dysfunction, we advance the hypothesis that elderly patients with MCR would achieve lower executive performance than non-MCR patients. Moreover, due to the suspected overlap between MCR and MCI syndromes, we hypothesize that this overlap could lead to a significant change in cognitive performance.

 

Objective

> To examine and compare cognitive performance of elderly patients living in the community, without dementia, both with and without MCR and MCI syndromes

 

Actions

  • Agreement to access the GAIT database
  • Analysis of the GAIT database
  • Authorship of an article in a scientific journal